Larry Husten, PHD

All posts by Larry Husten, PHD

August 27th, 2010

High-Risk PCI: Is an IABP Necessary?

Simon Redwood and Divaka Perera answer our questions about their randomized trial of IABP insertion during high-risk PCI in patients with severe LV dysfunction and extensive coronary disease. Check out our conversation and then ask them your own questions here.


August 27th, 2010

Door-to-Balloon vs. Total Health System Delay: Which Clock Matters Most?

Rick Lange brings the latest research on door-to-balloon times and moderates a free-flowing discussion with David Hillis, Harlan Krumholz, and Richard R. Schneider. Given regional variations, how do you think these patients should be treated? Tell us what you know here.


August 26th, 2010

Getting Ready for the ESC

The annual meeting of the European Society of Cardiology starts this weekend in Stockholm, and CardioExchange will be there. Associate Editor Anju Nohria will be blogging from the meeting, and I’ll be covering the most important news stories. Here are a few of the most-anticipated, late-breaking clinical trials.


August 25th, 2010

Studies Probe Cardiovascular Risks of Migraines

Two new studies in BMJ provide important new details about the elusive relationship between migraines and cardiovascular disease. In the first study, researchers in Iceland analyzed data from 18,725 middle-aged men and women who were followed for a median of 25.9 years. Larus Gudmundsson and colleagues found that people with migraine with aura were at […]


August 25th, 2010

Is There a Generation Gap in Cardiology?

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A brief posting in the Wall Street Journal Health Blog on the clash of generations in the medical workplace recently caught our attention. The Blog summarizes a commentary by Sharon Phelan in Obstetrics & Gynecology, which  posits that “different attitudes about work and life held by members of different generations can create tensions and clashes in the […]


August 24th, 2010

Questions About IABP During High-Risk PCI

CardioExchange welcomes Simon Redwood and Divaka Perera to discuss their randomized trial of routine intra-aortic balloon pump (IABP) insertion during high-risk PCI for the reduction of major adverse cardiac and cardiovascular events (MACCE) in patients with severe LV dysfunction and extensive coronary disease. Their study, which appears in the Journal of the American Medical Association, […]


August 24th, 2010

Study Suggests Prognostic Power of Dyspnea in Acute Heart Failure

Results of a study with the hormone relaxin suggest that a lack of ongoing dyspnea relief may be an important predictor of outcome. Marco Metra and fellow investigators in the Pre-RELAX-AHF study randomized 232 patients with acute heart failure to placebo or one of 4 doses of relaxin. Only 25% of all patients in the […]


August 23rd, 2010

AHA Science Advisory Calls for More Research on CVD in Asian-Americans

In a “Call to Action” contained in a new scientific statement, the American Heart Association says that more research is needed on cardiovascular disease in Asian-Americans. “Available research shows that subgroups of Asian-Americans are at increased risk of complications and death from cardiovascular disease; however, Asian-Americans are often studied as a group, which masks the differences […]


August 17th, 2010

Going Beyond Door-to-Balloon by Starting Earlier

Efforts to speed delivery of PCI to STEMI patients have focused on shortening the door-to-balloon time. Now a group of Danish researchers propose that efforts to improve care must include assessment of treatment from the time of the patient’s first contact with the emergency medical system. Analyzing historical data from 6209 MI patients who received […]


August 16th, 2010

A Treat for Chocolate Lovers from Sweden

In a report that will surely provide comfort to millions, a study of 31,823 Swedish women found that over 9 years of follow-up, women who regularly consumed moderate amounts of chocolate had a lower risk for developing heart failure than those who ate no chocolate at all. However, no protective effect was observed in women […]