Search Results for 'matsubara'

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April 10th, 2013

Scientific Misconduct: From Darwin and Mendel to Poldermans and Matsubara

Responding to recent episodes of scientific misconduct in cardiovascular research involving once prominent cardiovascular researchers, the editor of the European Heart Journal, Thomas Lüscher, has written an editorial discussing the significance of the new cases and placing them in a historical context that includes allegations of scientific misconduct by Mendel and Darwin, among many others. Lüscher writes that scientific misdoncuct […]


September 27th, 2013

Saying Sorry May Not Be Good Enough for Novartis

Novartis has issued a formal apology over misconduct relating to valsartan (Diovan) research in Japan, but that apology does not appear likely to satisfy the Japanese Health, Labor and Welfare Ministry, which plans to fully investigate the company’s role in the scandal. If necessary, ministry officials are prepared to raid the company’s offices in Japan. A Novartis official apologized to […]


September 5th, 2013

Lancet Formally Retracts Jikei Heart Study of Valsartan

The Lancet has formally retracted the Jikei Heart Study paper, originally published in 2007. The retraction had been widely anticipated for more than a month, after a series of news reports in Japan made it clear that the long-simmering controversy over scientific misconduct involving the Novartis blood pressure lowering drug valsartan (Diovan) had come to a full boil. […]


August 20th, 2013

A Pathway to Preventing Research Fraud

Is the road to fraud-free research paved with publicly accessible raw data?


July 30th, 2013

More Bad News for Valsartan

In the last few days, more bad news about valsartan (Diovan, Novartis) has emerged. Another major study conducted in Japan — the Jikei Heart Study — will be retracted, and Japanese health authorities said they were investigating severe skin reactions associated with use of the drug. The new events are only the latest problems for the drug […]


February 2nd, 2013

European Heart Journal Retracts Main Paper of the Kyoto Heart Study

The 2009 report of the Kyoto Heart Study on the add-on effect of valsartan in hypertension has been retracted with a terse comment by the editors of the European Heart Journal.


January 8th, 2013

Two Retractions for Embattled Chief Investigator of KYOTO HEART Study

The editor of Circulation Journal, the official journal of the Japanese Circulation Society (and not to be confused with the American Heart Association’s [AHA’s] better known Circulation) has announced the retraction of two substudies from the KYOTO HEART Study. The papers, according to the editor, “contain a number of serious errors in data analysis.” The announcement contained no additional information about […]


March 13th, 2012

Prominent Japanese Cardiologist Accused of Scientific Misconduct

Following accusations by independent bloggers in Japan and Germany, the American Heart Association (AHA) has issued an Expression of Concern about five papers published in AHA journals co-authored by Hiroaki Matsubara, a prominent cardiologist and researcher at Kyoto Prefectural University in Japan. In addition to his many papers exploring the basic science of the renin-angiotensin system, Matsubara was the […]