August 28th, 2013
American Heart Association Announces Late-Breaking Clinical Trials
Larry Husten, PHD
There are still a few days left in August, and the European Society of Cardiology meeting doesn’t start until this weekend in Amsterdam. Nevertheless, the American Heart Association has released the list of late-breaking clinical trials for its annual meeting in November.
Late-Breaking Clinical Trials 1: Acute Cardiovascular and Cerebrovascular Care
- Sunday, Nov 17, 2013, 4:00 PM – 5:19 PM
Moderators:
- Lance Becker, Philadelphia, PA
- Stephen Bernard, Melbourne, Australia
4:00 PM: Nitrites in Acute Myocardial Infarction
- Nishat Siddiqi, Univ of Aberdeen, Aberdeen, United Kingdom
- Discussant: Kenneth Bloch, Boston, MA
4:13 PM: Blood Pressure Reduction Among Acute Ischemic Stroke Patients: A Randomized Controlled Clinical Trial
- Jiang He, Tulane Univ, New Orleans, LA
- Discussant: Cathy A Sila, Cleveland, OH
4:35 PM: Randomized Clinical Trial of Pre-hospital Induction of Mild Hypothermia in Out-of-Hospital Cardiac Arrest Patients Using a Rapid Infusion of 4oC Normal Saline
- Francis Kim, Univ of Washington, Seattle, WA
- Discussant: Maaret Castrén, Stockholm, Sweden
4:57 PM: Target Temperature Management 33°C versus 36°C after Out-of-hospital Cardiac Arrest, a Randomized, Parallel Group, Assessor Blinded Clinical Trial
- Niklas Nielsen, Helsingborg Hosp, Lund Univ, Helsingborg, Sweden
- Discussant: Benjamin S Abella, Philadelphia, PA
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Late-Breaking Clinical Trials 2: Prevention: From Schools to Countries
- Monday, Nov 18, 2013, 9:00 AM -10:28 AM
Moderators:
- Donna K Arnett, Birmingham, AL
- Lynne Braun, Chicago, IL
9:00 AM: Promotion of Cardiovascular Health in Preschool Children: 36-month Cohort Follow-up
- Jaime Céspedes, Fundación CardioInfantil Insto de Cardiología, Bogotá, Colombia
- Discussant: Gerard R Martin, Washington, DC
9:22 AM: Randomized Trial of Social Network Lifestyle Intervention for Obesity: MICROCLINIC Intervention Results and 16-Month Followup
- Eric L Ding, Harvard Sch of Public Health, Boston, MA
- Discussant: Lawrence J Appel, Baltimore, MD
9:44 AM: Multifaceted Intervention to Improve Medication Adherence and Secondary Prevention Measures (Medication Study) After Acute Coronary Syndrome Hospital Discharge
- Michael Ho, VA Eastern Colorado Health Care System, Denver, CO
- Discussant: Nancy Albert, Cleveland, OH
10:06 AM: China Rural Health Initiative – Sodium Reduction Study: the Effects of a Community-Based Sodium Reduction Program on 24hr Urinary Sodium and Blood Pressure in Rural China
- Nicole Li, The George Inst for Global Health, Sydney, Australia
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Late-Breaking Clinical Trials 3: Medical and Surgical Approaches to Improving Heart Failure Outcomes
- Monday, Nov 18, 2013, 10:45 AM -12:13 PM
Moderators:
- Frederick A Masoudi, Aurora, CO
- Adrian F Hernandez, Durham, NC
10:45 AM: Atrial Antitachycardia Pacing and Managed Ventricular Pacing Reduce the Endpoint Composed by Death, Cardiovascular Hospitalizations and Permanent Atrial Fibrillation Compared to Conventional Dual Chamber Pacing in Bradycardia Patients: Results of the Minerva Randomized Study
- Giuseppe Boriani, Univ of Bologna, Policlinico S.Orsola-Malpighi, Bologna, Bologna, Italy
- Discussant: Anthony Tang, Victoria, BC, Canada
11:07 AM: Renal Optimization Strategies Evaluation in Acute Heart Failure (ROSE AHF) Trial
- Horng H Chen, MAYO Clinic, Rochester, MN
- Discussant: Marco Metra, Brescia, Italy
11:29 AM: Severe Ischemic Mitral Regurgitation: Is it Better to Repair or Replace the Valve?
- Michael A Acker, Hosp of the Univ of Pennsylvania, Philadelphia, PA
- Discussant: Timothy J Gardner, Newark, DE
11:51 AM: Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT)
- Marc A. Pfeffer, Brigham & Women’s Hosp, Harvard, Boston, MA
- Discussant: Margaret M Redfield, Rochester, MN
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Late-Breaking Clinical Trials 4: Therapeutic Advances in Coronary and Peripheral Vascular Disease.
- Monday, Nov 18, 2013, 3:45 PM – 5:13 PM
Moderators:
- John G Harold, Washington, DC
- Mark A Creager, Boston, MA
3:45 PM: One Year Mortality in STEMI Patients Randomized to Primary PCI or a Pharmaco-invasive Strategy. The Stream 1 Year Follow-up
- Peter Sinnaeve, Univ of Leuven, Leuven, Belgium
- Discussant: Harold Dauerman, Burlington, VT
4:07 PM: Secretory Phospholipase A2 Inhibition with Varespladib and Cardiovascular Events in Patients with an Acute Coronary Syndrome: Results of the VISTA-16 Study
- Stephen Nicholls, South Australian Health and Medical Res Inst, Adelaide, Australia
- Discussant: Philippe Gabriel Steg, Paris, France
4:29 PM: Randomized Comparison of Endovascular Revascularization Plus Supervised Exercise Therapy Versus Supervised Exercise Therapy Only in Patients With Peripheral Artery Disease and Intermittent Claudication: Results of the Endovascular Revascularization and Supervised Exercise (ERASE) Trial
- Farzin Fakhry, Erasmus MC, Rotterdam, Netherlands
- Discussant: Mary McDermott, Chicago, IL
4:51 PM: A Randomized Multicenter Clinical Trial of Renal Artery Stenting in Preventing Cardiovascular and Renal Events: Results of the CORAL Study
- Christopher J Cooper, Univ of Toledo, Toledo, OH
- Discussant: Thomas Zeller, Bad Krozingen, Germany
Late-Breaking Clinical Trials 5: New Strategies for Atrial Fibrillation Patients: Rhythm and Thrombosis
- Tuesday, Nov 19, 2013, 10:45 AM -12:03 PM
Moderators:
- Augustus O Grant, Durham, NC
- Keith A Fox, Edinburgh, United Kingdom
10:45 AM: RADAR-AF Trial. A Randomized Multicenter Comparison of Radiofrequency Catheter Ablation of Drivers versus Circumferential Pulmonary Vein Isolation in Patients with Atrial Fibrillation
- Felipe Atienza, Hosp Gregorio Maranon, Madrid, Spain
- Discussant: Mark Link, Boston, MA
11:07 AM: A Randomized Trial Comparing Genotype-Guided Dosing of Warfarin to Standard Dosing: The EU Pharmacogenetics of Anticoagulant Therapy (EU-PACT) Warfarin Study
- Munir Pirmohamed, Univ of Liverpool, Liverpool, United Kingdom
11:17 AM: The Clarification of Optimal Anticoagulation through Genetics (COAG) Trial
- Stephen E. Kimmel, Univ PA Sch of Med, Philadelphia, PA
11:27 AM: Discussant of EU-PACT Warfarin Study and COAG Trial: Patrick T. Ellinor, Boston, MA
11:41 AM: ENGAGE AF-TIMI 48 Primary Results
- Robert P Giugliano, Brigham and Women’s Hosp, Boston, MA
- Discussant: Elaine Hylek, Boston, MA
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