September 17th, 2010

Study Identifies MicroRNA Pattern Linked to Diabetes

Researchers in Britain and Europe have identified a microRNA pattern that may help identify people at risk for developing type 2 diabetes and who may go on to have cardiovascular events. “It’s very important for the clinician to define those diabetic patients who are at the highest risk of developing cardiovascular complications,” said the senior author of the Circulation Research paper, Manuel Mayr, in a press release issued by the American Heart Association. “We hope that this new class of blood markers may give additional insight that we’re currently not getting from the other clinical tests.”

In an accompanying editorial, Romano Regazzi writes that the study “unveils the existence of a plasma microRNA signature of diabetes.” He speculates on the possibility that “changes in the microRNA profile could not only signal the development of the disease but may also contribute to its manifestations,” suggesting the possibility of novel therapeutic interventions for diabetes.

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