February 16th, 2015
Cardiovascular Risk Calculators Overestimate
Larry Husten, PHD
Calculating cardiovascular risk has become a central and highly controversial component of cardiovascular guidelines. Now a study in the Annals of Internal Medicine finds that most of the commonly employed tools seriously overestimate the risk of people today. Researchers used data from 4,227 people enrolled in the Multi-Ethnic Study of Atherosclerosis (MESA) between 2000 and 2002 to assess the predictive […]
October 1st, 2014
Case: Testosterone Replacement Therapy and CV Risk
Seth D Bilazarian, MD, Anna Catino, MD and James Fang, MD
A 47-year-old man presents to the hospital reporting 4 days of chest pain that occurs during treadmill exercise, left-arm and jaw discomfort, and shortness of breath with diaphoresis. His medical history is noteworthy only for orthopedic surgeries and use of testosterone replacement therapy for reportedly low testosterone syndrome. He does not smoke and drinks alcohol only occasionally. He […]
February 15th, 2012
Mortality-Risk Calculators for AMI and Heart Failure Patients
Harlan M. Krumholz, MD, SM
Two mortality-risk calculators – one for patients with acute MI and another for those with heart failure – are now available for free at www.mortalityscore.org. The calculators are based on risk models produced by our research group at Yale for the Center for Medicare and Medicaid Services (CMS). The models are derived from Medicare administrative-claims […]
NEJM Journal Watch — Recent Cardiology Articles- Is Diltiazem Safe in Patients with AF Taking Apixaban or Rivaroxaban?
- Does Lowering High Childhood Lipid Levels Prevent Adverse Cardiovascular Events in Adulthood?
- Self-Expanding Supraannular Valve vs. Balloon-Expandable Valve in TAVR for Small Aortic Annulus
- A New TAVR Prosthesis for Aortic Regurgitation Shows Promise
- Aprocitentan, a Newly Approved Drug for Resistant Hypertension