The New England Journal of Medicine has published the first well-documented case of HIV pre-exposure prophylaxis (PrEP) failure despite good medication adherence. We heard lots of this information at CROI last year, and again I’m impressed at the extraordinary degree of virologic investigation done on a case from clinical practice. To refresh your memory, here are the critical details from the … Continue reading Case Report of PrEP Failure: What Can We Learn From It?