July 1st, 2011
Rivaroxaban (Xarelto) Gains First FDA Approval for DVT Prevention
Larry Husten, PHD
Rivaroxaban (Xarelto, Janssen) received FDA approval today for the prevention of deep-vein thrombosis in patients undergoing knee or hip replacement surgery. This oral anticoagulant has been approved for use at a 10-mg dose, once daily, for 35 days following hip replacement and for 12 days following knee replacement surgery.
The company has also submitted an application for the broader indication of the prevention of stroke and systemic embolism in AF patients.