CardioExchange Archive

Thoracic Endovascular Aortic Repair: The use of thoracic endovascular aortic repair (TEVAR) over open surgery to treat descending thoracic aortic disease has grown in recent years, despite a complete absence of randomized comparisons. In an expedited publication in the Journal of the American College of Cardiology, Cheng and colleagues report on a large systematic review and meta-analysis of 42 nonrandomized studies involving 5,888 patients. They conclude that TEVAR “may reduce early mortality and paraplegia compared with conventional open surgical management.” Despite the “important caveat” that their conclusions are based on observational studies, “the consistency of results across aortic pathologies, baseline age groups, and time periods of patient recruitment increases confidence that the findings are robust.”

Transcript of FDA Nebivolol Panel:The FDA posted on its website a transcript of the January 11 meeting