November 17th, 2009
At the AHA: Antiplatelet Therapy Following CABG
Larry Husten, PHD
During the Monday afternoon Late-Breaking Clinical Trials session, results of the CASCADE (Clopidogrel After Surgery For Coronary Artery Disease) trial were presented. The investigators randomized 113 CABG patients to aspirin plus clopidogrel versus aspirin alone. By 1 year of follow-up, there was no significant difference in the primary endpoint of vein graft intimal area or in the secondary endpoints of vein graft patency or adverse cardiovascular events.
