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Archive for January, 2011

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January 28th, 2011

Wow, That Was Fast: PrEP Guidelines Appear

With the ink barely dry on iPrEx — still tricky to type — along come “interim” guidelines from the CDC on pre-exposure prophylaxis (PrEP). Based on the results [iPrEx], CDC and other U.S. Public Health Service (PHS) agencies have begun to develop PHS guidelines on the use of PrEP for MSM at high risk for [...]


January 26th, 2011

Insurance Company Cheese Shop Redux

I had an interesting exchange with one of our nurses this week about a long-term patient of ours. The e-mails went something like this: Got a fax from —-’s insurance that his Lipitor won’t be covered anymore.  They will cover simvastatin, lovastatin, and pravastatin.  Let me know what you want to do. Charlie He’s on [...]


January 20th, 2011

A New Antiretroviral Drug Class, and a Movie

In my email in-box today was a very odd press release, referring to this paper, just published in PLoS ONE.  With the subject line, “Koronis – Clinical Trial Results Demonstrate Promise for First Non-suppressive HIV Drug,” it included the following information: Recently published Phase 2a clinical trial results show that the frequency of specific, drug-induced mutations in [...]


January 11th, 2011

Revised DHHS Guidelines, and Some Thoughts on Guidelines in General

As another major snow storm barrels in on us, you might have time over the next 24-48 hours to make some hot chocolate, throw some logs on the fire, and read the spanking-new 2011 Department of Health and Human Services (DHHS) HIV Treatment Guidelines, just posted here on the AIDSinfo web site. (Disclosure: I’m on [...]


January 6th, 2011

Thursday Thienamycins

Plenty going on in the ID, HIV, and (for the middle of winter) baseball worlds: Just out in CID, there’s a comprehensive review of Management of MRSA as part of the IDSA’s Practice Guidelines Series. Soft tissue infections, bacteremia, endocarditis, pneumonia, bone and joint infections, frequent relapses …  MRSA in all its painful glory. Some [...]


January 4th, 2011

HIV Year in Review Posted on Journal Watch

Want to catch up quickly in HIV clinical care? Forgive the bias, but the best strategy may well be to read our “Year in Review 2010” summary over on Journal Watch: AIDS Clinical Care. Always interesting to speculate what we’ll be choosing next year — I wouldn’t be surprised if progress in eradication (i.e., cure!) [...]


January 2nd, 2011

2011: A New Meaning for “Antiviral”

January 1, 2011 Dear Lake Superior State University, Clinicians are particularly concerned about this year’s “List of Words Banished from the Queen’s English for Mis-use, Over-use and General Uselessness“, as topping the list was the word, viral. One nominator said: Events, photographs, written pieces and even occasional videos that attracted a great deal of attention once [...]


HIV Information: Author Paul Sax, M.D.

Paul E. Sax, MD

Editor-in-Chief

NEJM Journal Watch HIV/Aids Clinical Care

Biography | Disclosures | Summaries

Learn more about HIV and ID Observations.