Archive for December, 2010
Paul Sax • December 22nd, 2010
Some items to consider in HIV/ID world as you dig into your salmonella-free holiday bird: Drug label change for stavudine (d4T): The label no longer has recommendations for dose-reduction in case of peripheral neuropathy, and cites data more strongly linking d4T use to lipoatrophy. The strategy of decreasing the dose to reduce d4T toxicity hasn’t [...]
Paul Sax • December 17th, 2010
First, who was Berlin Patient I? Second, over in the journal Blood is the latest update on Berlin Patient II, the guy apparently cured of HIV by bone marrow transplantation: We have previously reported the case of an HIV-infected patient in whom viral replication remained absent despite discontinuation of antiretroviral therapy after transplantation with CCR5Δ32/Δ32 [...]
Paul Sax • December 13th, 2010
I absolutely love the journal Clinical Infectious Diseases. It’s easily my second-favorite journal. (Can you guess my favorite? Perhaps this new “About this blog” section will give you a hint.) But back to CID — here’s why I love it: Great content. Seems every issue has fascinating studies, usually of great clinical relevance to the [...]
Paul Sax • December 9th, 2010
Over at the Chicago Tribune, there is this superb review of the Chronic Lyme disease issue. Lyme disease is real. The bacterial infection, chiefly transmitted by deer ticks, can cause rashes, swollen joints and inflamed nerves, and usually is curable with a round of antibiotics. But doctors around the country are telling patients with common [...]
Paul Sax • December 6th, 2010
During Thanksgiving, my brother-in-law — who is a professional musician and also a passionate history buff — gave me a scholarly paper to review on the strange death of the famous American explorer Meriwether Lewis, of “Lewis and Clark” fame. The bottom line? Lewis may well have had neurosyphilis — at least that’s the premise of [...]
Paul Sax • December 1st, 2010
A few random thoughts on this 2010 World AIDS Day. Now you can mark your calendars for the next three International AIDS Society/World AIDS Meetings: 2011 in Rome, 2012 in Washington, DC — and now, 2013 in Kuala Lumpur, Malaysia. And what do all 3 of these cities have in common? Extreme summer heat! (For Kuala Lumpur, it’s [...]