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Posts Tagged ‘ritonavir’

Sedating HIV-Infected Endoscopy Patients

M. Brian Fennerty • March 14th, 2009

Categories: Endoscopy, Patient care

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In a recent blog post, ID expert Paul Sax raised the question of which sedatives should be used when scoping HIV-infected patients on ritonavir or efavirenz. Both antiretrovirals inhibit the CYP3A enzyme, which metabolizes one of our most commonly used sedatives, midazolam. Use of midazolam with either antiretroviral is technically contraindicated because of significant increases [...]